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Acute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels
This book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/...
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| Format: | e-Book |
| Language: | English |
| Published: |
Cham :
Springer International Publishing :
2018.
Imprint: Springer, |
| Edition: | 1st ed. 2018. |
| Series: | Springer Theses, Recognizing Outstanding Ph.D. Research,
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| Online Access: | Full-text access |
| Summary: | This book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/magneto-genetics. The author also reports on two platforms-magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria-that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations. This thesis was submitted to and approved by the University of California, Los Angeles. Introduces technology for non-invasive control of neural activities that offer deep tissue penetration and controllable dosage; Examines the effects of biomechanical forces on cellular functions; Explores how to improve the reproducibility and uptake of magnetic tools for non-invasive neural modulation. |
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| Physical Description: | XVII, 119 p. 33 illus., 32 illus. in color. online resource. |
| ISBN: | 9783319690599 |
| ISSN: | 2190-5061 |
| DOI: | 10.1007/978-3-319-69059-9 |