Molecular Recognition of DNA Double Helix Gene Regulation and Photochemistry of BrU Substituted DNA /

In this book, the molecular recognition of DNA using small molecules is discussed, with a study of the photochemistry of BrU-labeled DNA. The purposes of the study were to develop small molecules for regenerative medicine, to develop a method to detect the recognition site of small molecules, and to...

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Detaylı Bibliyografya
Yazar: Saha, Abhijit (Yazar)
Müşterek Yazar: SpringerLink (Online service)
Materyal Türü: e-Kitap
Dil:İngilizce
Baskı/Yayın Bilgisi: Singapore : Springer Nature Singapore : 2018.
Imprint: Springer,
Edisyon:1st ed. 2018.
Seri Bilgileri:Springer Theses, Recognizing Outstanding Ph.D. Research,
Konular:
Bioorganic chemistry.
Biomaterials.
Nucleic acids.
Regenerative medicine.
Bioorganic Chemistry.
Nucleic Acid.
Regenerative Medicine and Tissue Engineering.
Online Erişim:Full-text access
İçindekiler:
  • 1. Overview of DNA minor groove binding synthetic small molecules and photochemistry of BrU substituted DNA
  • 2. Synthesis and Biological Evaluation of Targeted Transcriptional Activator with HDAC8 Inhibitory Activity
  • 3. Chemical Modification of a Synthetic Small Molecule Boosts its Biological Efficacy against Pluripotency Genes in Mouse Fibroblast
  • 4. Development of a novel photochemical detection technique for the analysis of polyamide binding sites
  • 5. Examining cooperative binding of Sox2 on DC5 regulatory element upon complex formation with Pax6 through excess electron transfer assay
  • 6.UVA irradiation of BrU-substituted DNA in the presence of Hoechst 33258. .

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