Engineering a Robust DNA Circuit for the Direct Detection of Biomolecular Interactions

This book provides essential insights into designing a localized DNA circuit to promote the rate of desired hybridization reactions over undesired leak reactions in the bulk solution. The area of dynamic DNA nanotechnology, or DNA circuits, holds great promise as a highly programmable toolbox that c...

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Detaylı Bibliyografya
Yazar: Yan Shan, Ang (Yazar)
Müşterek Yazar: SpringerLink (Online service)
Materyal Türü: e-Kitap
Dil:İngilizce
Baskı/Yayın Bilgisi: Singapore : Springer Nature Singapore : 2018.
Imprint: Springer,
Edisyon:1st ed. 2018.
Seri Bilgileri:Springer Theses, Recognizing Outstanding Ph.D. Research,
Konular:
Biotechnology.
Bioinformatics.
Microtechnology.
Microelectromechanical systems.
Chemical Bioengineering.
Computational and Systems Biology.
Microsystems and MEMS.
Online Erişim:Full-text access
İçindekiler:
  • Introduction
  • Literature Review
  • Materials and Methods
  • Modular Framework for Engineering a Self-Contained DNA Circuit
  • Designing Hybridization Chain Reaction Monomers for Robust Signal Amplification
  • Design Concepts in Association Toehold for Robust Signal Transduction
  • DNA Split Proximity Circuit as a General Platform for Interrogating Biomolecular Events
  • DNA Split Proximity Circuit for Visualizing Cell Surface Receptor Clustering- A Case Study Using Human Epidermal Growth Factor Receptor Family
  • Conclusion and Future Outlooks.

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