A Network-Based Approach to Cell Metabolism From Structure to Flux Balances /

This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures. The results reported here have a potential application in areas like metabolic engineering and disease treatment...

Ful tanımlama

Detaylı Bibliyografya
Yazar: Güell, Oriol (Yazar)
Müşterek Yazar: SpringerLink (Online service)
Materyal Türü: e-Kitap
Dil:İngilizce
Baskı/Yayın Bilgisi: Cham : Springer International Publishing : 2017.
Imprint: Springer,
Edisyon:1st ed. 2017.
Seri Bilgileri:Springer Theses, Recognizing Outstanding Ph.D. Research,
Konular:
Biotechnology.
Bioinformatics.
Physical chemistry.
Chemical Bioengineering.
Computational and Systems Biology.
Physical Chemistry.
Online Erişim:Full-text access
İçindekiler:
  • Cellular Metabolism at the Systems Level
  • Methods and Data
  • Structural Knockout Cascades in Metabolic Networks
  • Effects of Reaction Knockouts on Steady States of Metabolism
  • Detection of Evolution and Adaptation Fingerprints in Metabolic Networks
  • Assessing FBA Optimal States in the Feasible Flux Phenotypic Space
  • Conclusions.

Benzer Materyaller