Study of the Calcium Regulation Mechanism of TCR Activation Using Nanodisc and NMR Technologies

This thesis describes the use of biophysical and biochemical methods to prove that calcium has a positive feedback effect on amplifying and sustaining CD3 phosphorylation and should enhance T-cell sensitivity to foreign antigens. The study presented shows that calcium can regulate the signal pathway...

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Bibliographic Details
Main Author: Bi, Yunchen (Author)
Corporate Author: SpringerLink (Online service)
Format: e-Book
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : 2018.
Imprint: Springer,
Edition:1st ed. 2018.
Series:Springer Theses, Recognizing Outstanding Ph.D. Research,
Subjects:
Biomedical engineering.
Biophysics.
Biological transport.
Cell membranes.
Immunology.
Atomic structure  .
Molecular structure .
Biomedical Engineering and Bioengineering.
Membrane Trafficking.
Atomic and Molecular Structure and Properties.
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