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Mechanism of Functional Expression of the Molecular Machines
This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor...
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| Müşterek Yazar: | |
| Materyal Türü: | e-Kitap |
| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
Singapore :
Springer Nature Singapore :
2016.
Imprint: Springer, |
| Edisyon: | 1st ed. 2016. |
| Seri Bilgileri: | SpringerBriefs in Molecular Science,
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| Konular: | |
| Online Erişim: | Full-text access |
| Özet: | This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system. |
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| Fiziksel Özellikler: | X, 70 p. 30 illus., 24 illus. in color. online resource. |
| ISBN: | 9789811014864 |
| ISSN: | 2191-5415 |
| DOI: | 10.1007/978-981-10-1486-4 |