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Structure and Function of GPCRs
This book introduces readers to the latest advances in G protein-coupled receptor (GPCR) biology. It reviews our current understanding of the structural basis of ligand binding and allosteric mechanisms, following a decade of technological breakthroughs. Several examples of structure-based drug disc...
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| Diğer Yazarlar: | |
| Materyal Türü: | e-Kitap |
| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
Cham :
Springer International Publishing :
2019.
Imprint: Springer, |
| Edisyon: | 1st ed. 2019. |
| Seri Bilgileri: | Topics in Medicinal Chemistry,
30 |
| Konular: | |
| Online Erişim: | Full-text access |
İçindekiler:
- Structures of Non-rhodopsin GPCRs Elucidated Through X-Ray Crystallography
- NMR Spectroscopy for the Characterization of GPCR Energy Landscapes
- Structure and Activation Mechanism of GPCRs
- Structure-Based Discovery of GPCR Ligands from Crystal Structures and Homology Models
- Integration on Ligand and Structure Based Approaches in GPCRs
- Biased Agonist Pharmacochaperones: Small Molecules in the Toolbox for Selectively Modulating GPCR Activity
- Endosomal PTH Receptor Signaling Through cAMP and Its Consequence for Human Medicine
- Structure and Function Studies of GPCRs by Site-Specific Incorporation of Unnatural Amino Acids
- Fluorescent-Based Strategies to Investigate G Protein-Coupled Receptors: Evolution of the Techniques to a Better Understanding
- Modulation of Metabotropic Glutamate Receptors by Orthosteric, Allosteric, and Light-Operated Ligands. .