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Molecular Dynamics Analyses of Prion Protein Structures The Resistance to Prion Diseases Down Under /
Unlike bacteria and viruses, which are based on DNA and RNA, prions are unique as disease-causing agents since they are misfolded proteins. Prion diseases are called "protein structural conformational" diseases. This monograph is the book on molecular dynamics (MD) simulations nearly for a...
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| Müşterek Yazar: | |
| Materyal Türü: | e-Kitap |
| Dil: | İngilizce |
| Baskı/Yayın Bilgisi: |
Singapore :
Springer Nature Singapore :
2018.
Imprint: Springer, |
| Edisyon: | 1st ed. 2018. |
| Seri Bilgileri: | Focus on Structural Biology,
10 |
| Konular: | |
| Online Erişim: | Full-text access |
İçindekiler:
- Preface
- Basic Knowledge
- Part I Prion Resistance Species
- Rabbits -Wild-type and Mutants
- Dogs -Wild-type and D159NMutant
- Horses, Buffaloes, and Pigs
- Chicken, Turtles, and Frogs
- Other Species
- Part II b 2-a2 Loop
- Wild-type Mouse 37 oC and 19.85 oC Structures
- Mouse Mutants
- Other Species with an Ordered b 2-a2
- Part III Human Mutants
- Human Mutants
- Human PrPC Monomer, Dimer and Its M129V Mutant
- Human Peptides
- Part IV PrP Binding/Docking
- PrP Bounded to Antibodies, Nanobody, RNA aptamer, etc
- Potential Antiprion Drugs
- Part V Prion Peptides with Cross-b Structures
- Mathematical Formulas for All PrP Peptides' cross-b structures
- Hydrogen Bonds Between Two Optimized Fundamental Chains of Each Model
- References. .