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Total Synthesis of Natural Products with Antimicrobial Activity

This thesis focuses on the development of efficient and scalable total syntheses of natural products that can be used as preferred scaffolds for anti-infective drug discovery. It describes the total synthesis of two classes of antimicrobial non-ribosomal peptides (NRPs) - teixobactin and the skyllam...

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Bibliographic Details
Main Author: Giltrap, Andrew (Author)
Corporate Author: SpringerLink (Online service)
Format: e-Book
Language:English
Published: Singapore : Springer Nature Singapore : 2018.
Imprint: Springer,
Edition:1st ed. 2018.
Series:Springer Theses, Recognizing Outstanding Ph.D. Research,
Subjects:
Online Access:Full-text access
Table of Contents:
  • Introduction
  • Total Synthesis of Teixobactin
  • Synthesis of Deshydroxy Skyllamycins A-C
  • Total Synthesis of Skyllamycins A-C
  • Experimental.